BELOTERO DERMA FILLER

What is the most important information I should know about BELOTERO DERMA FILLER?
Introduction of BELOTERO DERMA FILLER into the vasculature may lead to embolization, occlusion of the vessels, ischemia, or infarction. Take extra care when injecting soft tissue fillers, for example inject the product slowly and apply the least amount of pressure necessary. Rare but serious adverse events associated with the intravascular injection of soft tissue fillers in the face have been reported and include temporary or permanent vision impairment, blindness, cerebral ischemia or cerebral hemorrhage, leading to stroke, skin necrosis, and damage to underlying facial structures. Immediately stop the injection if a patient exhibits any of the following symptoms, including changes in vision, signs of a stroke, blanching of the skin, or unusual pain during or shortly after the procedure. Patients should receive prompt medical attention and possibly evaluation by an appropriate health care practitioner specialist should an intravascular injection occur.

As with all events that involve an injection through the skin, there is a risk of infection. Laser treatments or chemical peels or any other treatments that affect the skin can increase the risk of infection. Do not use BELOTERO DERMA FILLER if you have a skin inflammation or a skin infection. Do not use until the infection is healed.

Patients getting BELOTERO DERMA FILLER may have an injection site reaction. These reactions can include inflammation and usually last less than seven days.

For approximately 24 hours after treatment, avoid:

• strenuous activity
• extensive sun or heat exposure
• aspirin or non-steroidal anti-inflammatory drugs
• alcoholic beverages

 

Exposure to any of the above can cause temporary redness, swelling, and/or itching at the injection site.

It is not known how BELOTERO DERMA FILLER will work in areas of the face other than the smile lines. It is not known how BELOTERO DERMA FILLER will work in women who are pregnant or breastfeeding or people who are less than 21 years of age.

What should I tell my doctor before injections with BELOTERO DERMA FILLER?

Tell your doctor if you are taking medicines that affect blood clotting, like aspirin, an NSAID or warfarin.  These medicines may put you at an increased risk of bruising or bleeding at the treatment site. Tell your doctor if you have a skin reaction like cold sores, cysts, pimples, rashes, hives, or an infection. Treatment with BELOTERO DERMA FILLER should be delayed until the reaction goes away. Tell your doctor if you are taking medicines that affect your immune system.

What are the most common adverse events seen with BELOTERO DERMA FILLER?

The most common adverse events seen in clinical studies with BELOTERO DERMA FILLER were swelling, bruising, redness, hardening of the skin, pain, altered color, or itching. Other side effects that have occurred in clinical studies of BELOTERO DERMA FILLER include headache, swelling of the side of the nose, moderate cold sore, lip numbness, and lip dryness. Side effects were often mild to moderate and often resolved within 7 days.